Malaria vaccine development.
نویسندگان
چکیده
منابع مشابه
Advances and challenges in malaria vaccine development.
Malaria caused by Plasmodium falciparum remains a major public health threat, especially among children and pregnant women in Africa. An effective malaria vaccine would be a valuable tool to reduce the disease burden and could contribute to elimination of malaria in some regions of the world. Current malaria vaccine candidates are directed against human and mosquito stages of the parasite life ...
متن کاملMalaria Vaccine Development: A Step Towards Reality
Citation: Muktikesh Dash. “Malaria Vaccine Development: A Step Towards Reality”. EC Microbiology 2.3 (2015): 294-295. Malaria, a protozoan parasitic disease caused by five species of Plasmodium i.e., P. vivax, P. falciparum, P. malariae, P. ovale and P. knowlesi in humans. Nearly half of the world’s population, an estimated 3.3 billion people in 97 countries and territories are at risk of malar...
متن کاملPrime-boost strategies for malaria vaccine development.
Malaria is an intracellular pathogen, for which an effective vaccine is likely to require induction of cell-mediated immunity. Immunisation approaches that stimulate strong and persistent levels of effector T-cells are being sought by many researchers. DNA vaccines, recombinant protein and viral vectors were amongst the vaccine delivery systems that appeared promising for the generation of cell...
متن کاملStatus of vaccine research and development of vaccines for malaria.
Despite recent progress in reducing deaths attributable to malaria, it continues to claim approximately 500,000 lives per year and is associated with approximately 200 million infections. New tools, including safe and effective vaccines, are needed to ensure that the gains of the last 15 years are leveraged toward achieving the ultimate goal of malaria parasite eradication. In 2015, the Europea...
متن کاملA review of human vaccine research and development: malaria.
The last several years have seen significant progress in the development of vaccines against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria infection and disease was demonstrated in African children. Pursued by various groups and on many fronts, several other candidate vaccines are in early clinical trials. Yet, despite the optimism and promise, an effective...
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ژورنال
عنوان ژورنال: Clinical Microbiology Reviews
سال: 1994
ISSN: 0893-8512,1098-6618
DOI: 10.1128/cmr.7.3.303-310.1994